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Hair restoration and growth

DrSkin hair restoration

For those with a more severe type of hair loss, alopecia or thinning hair, the treatment with Hair Fillers can be an outcome. Hair Filler is an injectable, based on a patented formula 0f 7 peptides and hyaluronic-acid, for the revitalisation of hair and scalp. Hair Filler can help to decrease hair loss and be effective in the treatment of hair regrowth. The product is the result of 13 years R&D by Caregen and was successfully launched in 2016. 
This peptide-hyaluronic acid treatment ensures in many cases for the reversal of the hair loss process and at the same time revitalizes the scalp and hair follicles to stimulate hair regrowth. The formula of patented peptides and hyaluronic acid strengthens the hair into the hair follicles, leading according to clinical research to more, thicker and stronger hair.


The right candidates for a treatment with Hair Filler are:

  • Men and women suffering from any type of non-scarred alopecia

  • Men and women of any age with overall thinning and weaker hair

  • Men and women with excessive hair loss

  • Men and women who want to increase the chance of survival of their hair transplantation

  • Alopecia patients who want to create extra effect in combination with other hair treatments

How does it works?

In order to make hair regrowth, it would be necessary to upregulate the expression of genes and proteins that are essential for hair growth, and to downregulate the expression of genes and proteins that are involved in hair loss.

Hair Filler contains 7 patented peptides. Every peptide has shown its efficacy in the hair regrowth and loss process by different in-vitro tests performed by Caregen.

Hair Filler promotes blood circulation in the scalp and helps the follicles to revitalize and cause stronger hair regrowth.

This sustained release technology enhanced the efficacy of the 7 peptides for two weeks by a constant and regulated release and penetration of these active ingredients into the skin.

Several in-vitro tests performed by Caregen shows the following efficacy per peptide:

  1. Decapeptide-10 (CG-Keramin2): would provide nourishment to scalp and hair root for a healthier and thicker hair shaft through the stimulus of angioedema.

  2. Octapeptide-11 (CG-Seperin): would inhibit cell death in hair cells caused by oxidative stress (excess free radicals)

  3. Octapeptide-2 (Prohairin-β4): would promote hair growth by activating the stem cells in hair follicles

  4. Decapeptide-18 (CG-WINS): would lead to the formation of hair placodes and generates new hair follicles by β-catenin and the SHH signal.

  5. Decapeptide-28 (CG-Rehairin): would stimulate hair follicles, activates the anagen phase, slows down the categene phase to inhibit hair loss.

  6. Oligopeptide-54 (CG-Nokkin): would inhibit hair loss by the down-regulation of DKK-1, BMP4 and TGFβ-1 signal

  7. Oligopeptide-71 (CG-Edrin): would promote hair regrowth by activating the WNT signal

How many sessions needed?

Each person and hair problem is different and therefore responds differently to a treatment. Your doctor will be able to advise you on this. Clinical study by Caregen shows that good results are obtained with the treatment frequency below.

  • STANDARD Hair Filler Treatment: 1 session per 2 weeks, for 8 weeks (total of 4 sessions)

  • INTENSIVE Hair Filler Treatment: 1 session per 2 weeks, for 8 weeks (total 4 sessions), then 1 monthly maintenance session for 3-6 months.

How long is the hair filler treatment is visible?

The effect of the Hair Filler treatment differentiates per patient, but could be visible for around one year. In between and after this period, the Hair Filler therapy could be (partly) repeated.

Benefits of hair filler

Hair Filler therapy increases the chance to:

  • inhibit hair loss

  • stimulate hair regrowth

  • increase  hair density and hair thickness

  • revitalize hair follicles and hair cells

  • stimulate blood circulation and hydration in the scalp

Potential side effects

Possible side effects of Hair Filler:

  • Transient short duration pain may occur following wounded scalp introduction

  • Redness, swelling, edema, hematomas, itching and slight pain at the injection area can occur following treatment and generally subside over 72 hours

  • Allergy to any of the ingredients.

The potential risk of  these side effects shall be explained to the patient by the practitioner. All side effects other than those described above or persisting for more than one week must be reported to the practitioner by the patient.

Hair restoration and growth: FAQ
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